How should prostate specific antigen be interpreted?
نویسندگان
چکیده
منابع مشابه
How should prostate specific antigen be interpreted?
Since from its clinical introduction to the present time, measurement of serum prostate specific antigen (PSA) level is one of the most widely used tests in urology practice. Initially, the upper limit for PSA was 4 ng/mL, but today, a reduction for the upper limit is recommended to 2.5-3 ng/mL for patients between 60 and 65 years of age and younger. On the use of PSA as a screening test for pr...
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P rostate-specific antigen (PSA) is the most widely used biomarker for prostate cancer, but may also be elevated in nonmalignant conditions such as benign prostatic hyperplasia. Studies in the early 1990s suggested that rapid increases in PSA over time—a concept known as PSA velocity (PSAV)—may be useful to distinguish prostate cancer from the generally slower rise in PSA that may be seen in be...
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Background: It is relevant to highlight that there is not a precise and perfect report on either 95 percentile value (upper limit of normal range) or on appropriate reference intervals for serum PSA in Iranian population. Objective: To determine age-specific reference ranges for serum prostate-specific antigen (PSA) concentration and PSA density (PSAD) and prostate volumes in a population of he...
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Appropriate methods for meta-regression applied to a set of clinical trials, and the limitations and pitfalls in interpretation, are insufficiently recognized. Here we summarize recent research focusing on these issues, and consider three published examples of meta-regression in the light of this work. One principal methodological issue is that meta-regression should be weighted to take account...
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Introduction: As a glycoprotein, Plasma Prostate-Specific Antigen (PSA) is mainly produced by prostate epithelial cells and is used as a major diagnostic tool for prostate cancer. A group of researchers relate the elevated number of estrogen receptors in breast cancer samples to the over-production of PSA in this type of cancer. Therefore, the present study aimed to determine the participants' ...
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ژورنال
عنوان ژورنال: Türk Üroloji Dergisi/Turkish Journal of Urology
سال: 2014
ISSN: 1300-5804,1308-4631
DOI: 10.5152/tud.2013.038